A cancer-linked protein called BRAF may help drive chronic nerve pain, and existing cancer drugs targeting it reduced pain sensitivity in preclinical models.
Chronic nerve...
A single injection of a nanoparticle treatment engineered to encourage the generation of new brain cells was enough to reverse cognitive decline in an...
An injectable hydrogel platform forms a lubricating depot inside the joint after a single minimally invasive injection, allowing drug-loaded nanocarriers to remain in place...
Stanford Medicine researchers and colleagues found a way to make natural killer cells better at attacking cancer. In mice, the enhanced cells entered solid...
U.S. poison centers have recorded a sharp long-term rise in liver injuries linked to medications and other foreign substances, with most severe enough to...
For the first time, new imaging technology in Scotland allows scientists to track cancer from the whole body down to individual cells, providing new...
Researchers have developed a compound that attacks cancer cells in two ways by exploiting their demand for sugar while blocking their backup fuel supply.
Cancer...
A protein called TRAILshort may act as a central immune brake that limits T-cell responses and CAR-T therapy.
Cancer cells can weaken the immune system...
T cells may use a previously unknown CD64-dependent pathway to attack acute myeloid leukemia.
T cells are generally thought to identify cancer through a well-established...
Engineered gut bacteria helped activate immune attacks against pancreatic tumors in animal models.
Pancreatic tumors are notoriously difficult for the immune system to attack. They...
NIH-supported findings reveal a previously unknown aspect of human brain aging that may contribute to cognitive decline and dementia risk later in life.
Beginning in...
A large international study suggests that very high p-tau217 levels may identify cognitively healthy adults who face a substantially greater chance of impairment years...
Focused ultrasound helped deliver microRNAs that targeted multiple glioblastoma genes and improved outcomes in animal models.
A treatment aimed at glioblastoma must first cross one...
An experimental drug repaired the gut and reversed severe fatty liver disease in animals, opening the door to a promising new treatment for MASH.
Researchers...